Animal Phenotyping Core

The Animal Phenotyping Core (APC) enables investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. The phenotyping capabilities of the APC range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue. In addition to the service provided, the APC provides expertise to guide both new and experienced investigators in the selection and use of techniques to define metabolic and related phenotypes.


Adipose Tissue Morphology & Function Energy Intake & Expenditure Body Composition Analysis Metabolic Surgery

Histologic and Morphometric Analysis

Indirect calorimetry plus food intake

Body Composition in Conscious Animals – MRI Analysis

Bariatric Surgery

Primary Cell Isolation and Analysis

Feeding behavior

Body Composition and Bone Density – DEXA Analysis

Autonomic denervations

Differentiation of Adipocytes and Adipose Tissue Macrophages

Exercise calorimetry

Body Composition and Distribution - MicroCT Analysis

Gastrointestinal tube feeding

Metabolic Function of Adipose Tissue

Temperature challenge and core body temperature measurements


Stereotactic brain cannulations & injections

Adipose Tissue Transplantation



Bone marrow transplantation



  • Yiying Zhang, PhD

    • Associate Director
  • Anthony Ferrante Jr. MD, PhD

    • Associate Director
  • Kaiying Guo, BS

    • Technician
  • Licheng Wu, MA

    • Technician

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